Which disease is not typically associated with mosquitoes as vectors?

Lyme disease is primarily transmitted through the bite of infected black-legged ticks, not mosquitoes. The disease is caused by the Borrelia bacteria, which ticks acquire from feeding on infected animals, such as deer and mice. This makes Lyme disease distinct from the other options, which all involve diseases spread by mosquito vectors.

Dengue fever, West Nile virus, and malaria are all illnesses that have a strong relationship with mosquitoes. Dengue fever is caused by a virus transmitted through the Aedes aegypti mosquito. West Nile virus, which can cause neurological illness in humans, is also spread by mosquitoes, particularly Culex species. Malaria is caused by Plasmodium parasites and is transmitted to humans through the bites of infected Anopheles mosquitoes. The distinction of Lyme disease in the context of mosquito-borne diseases highlights the role of different vectors in the transmission of various infectious diseases.